Iran Press/America: The Brazilian health ministry said 2,286 deaths were registered in the last 24 hours.
The previous record had been set on Tuesday with 1,954 deaths.
The grim figure put Brazil's total death toll at more than 270,000.
Earlier Wednesday, President Jair Bolsonaro, who has long downplayed the risks of the virus, wore a mask in an event at the presidential palace in capital Brasilia for the first time in months.
He also sanctioned a bill that makes the purchase of COVID-19 vaccines easier.
So far less than 5 percent of Brazilians have been gotten their shots against the disease.
The global tally of coronavirus cases stands at 118,638,000. While 94,251,000 have recovered,2,632,000 have died so far.
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