An emergency services spokesman was quoted by state TV as saying the plane crashed in a mountainous area and caught fire.
The plane reportedly went down near the city of Shahr-e Kord, about 400 kilometres south of Tehran..
"We can confirm that a Turkish private jet ... while passing through our airspace disappeared from the radar and crashed near Shahr-e Kord," Civil Aviation Organisation spokesman Reza Jafarzadeh told state television.