Iran Press/ America: Midfielder Guido Rodriguez scored the only goal at the Mané Garrincha stadium in Brasilia with a header in the 13th minute after Messi crossed from the left. The ball hit goalkeeper Fernando Muslera's right post before going in.
Lionel Messi's team is now co-leaders of Group A with Chile with four points each.
Earlier Chile beat Bolivia 1-0 on a goal by English-Chilean striker Ben Brereton.
Seeking some defensive solidity, Argentina changed nearly all of back four after the 1-1 draw with Chile. Right-back Gonzalo Montiel, defender Lucas Martínez Quarta and left-back Nicolás Tagliafico were replaced by Nahuel Molina, Cristian Romero and Marcos Acuña, respectively. Nicolás Otamendi was the only defender who remained. Rodriguez replaced injured Leandro Paredes.
The 2021 Copa America, the 47th edition of the Copa América, is being held without public attendance in Brazil.
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