At the emergency demonstration called by the Palestine Solidarity Campaign (PSC), Palestinians and activists urged the UK government to condemn the killings.
“Gaza, Stop the Massacre”, “End the Siege”, and “Stop Israeli State Slaughter,” read some of the placards held by protesters.
The demonstration in London followed a vigil held at Parliament Square for those who lost their lives in Gaza, which some MPs also joined.
“Thank you for standing up for the besieged people of Gaza,” the PSC quoted a speaker as saying during the demonstration.
“The siege needs to come to an end! There will never be peace until refugees can go home. There will never be peace without Jerusalem as the capital of Palestine.”
“The brutality of the Israeli Army has been laid bare for all to see. We stand in solidarity with the people of Palestine, but words alone are not enough,” Sinn Fein MP Chris Hazzard said at the demonstration.
“The international community cannot continue to stand idly by. Israel must be held to account for its illegal actions,” he said.
“Sinn Fein calls on the Irish government to take a lead internationally on this. There can be no impunity for barbaric state violence directed at peaceful protests.”
Since the border rallies began on March 30, more than 120 Palestinian demonstrators have been killed by cross-border Israeli gunfire, according to the Palestinian Health Ministry.
Similar protests were held in Birmingham, Bristol, Manchester, Cardiff, Glasgow, Newcastle, Nottingham, Oxford and Sheffield.