Iran Press/Asia: The blast took place near Green Village, a large compound that houses aid agencies and international organisations, interior ministry spokesman Nasrat Rahimi said.
It came while Afghanistan's main TV station Tolo News aired an interview with the US envoy Zalmay Khalilzad, who was discussing a potential deal with the Islamist extremist Taliban that would see the US withdraw forces from five bases across Afghanistan, AFP reported.
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Gunfire could be heard in the aftermath along with a secondary explosion when a nearby petrol station caught fire, sending plumes of smoke into the night sky.
Taliban spokesman Zabihullah Mujadid said a coordinated attack with a suicide bomber and gunmen was under way.
Khalilzad was in Kabul following the latest round of talks with the Taliban in Doha, Qatar, after which he said the two sides were at the "threshold" of a deal.
He met Monday with Afghan President Ashraf Ghani and showed him the draft of a proposed agreement.
The prospective deal centres on US troop reductions in return for several security guarantees from the Taliban, as well as broader peace talks between the insurgents and the Afghan government and an eventual ceasefire.
Still, even if many of the 13,000 or so US troops in Afghanistan leave soon after a final deal, President Donald Trump last week said America would maintain a permanent presence - with 8,600 troops initially.
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