"I'm saying it very clearly, this deal is not dead. There were numerous signatories. The United States withdrew. France, Great Britain, Germany, China and Russia are still part of it," Jean-Yves Le Drian said.
He went on to say, "We also disagree with the method because this collection of sanctions which will be set up against Iran will not enable dialogue."
France's foreign minister was speaking two days after U.S. Secretary of State Mike Pompeo said Washington would impose "the strongest sanctions in history" if Iran did not curb its regional influence and limit its ballistic missile program.
Speaking weeks after the United States' move to pull out from a nuclear agreement Iran signed with major powers in 2015, Pompeo laid out 12 tough conditions for any "new deal" with Tehran.
Following Pompeo's remarks on Monday, Iranian President Hassan Rouhani said the United States cannot make decisions for Iran and other independent countries.
Iran has said it would remain in the JCPOA for now, pending negotiations with the other signatories in the coming weeks, before making a final decision on its future role in the agreement.