More than 75,000 employees at Kaiser Permanente began one of the largest healthcare worker strikes in recent US history on Wednesday after failing to resolve a dispute over staffing levels.

Iran PressAmerica: More than 75,000 employees at Kaiser Permanente began one of the largest healthcare worker strikes in recent US history on Wednesday after failing to resolve a dispute over staffing levels.

The walkout at America's largest non-profit healthcare organization comes during a year in which an inflation surge has spurred strike action to demand higher pay across the United States, from Hollywood to Detroit.

The strike of union members at Kaiser Permanente began early Wednesday at sites in Virginia and the US capital Washington.

The walkout will be "the largest healthcare worker strike in US history," the Coalition of Kaiser Permanente Unions, an umbrella group representing local unions, said in a statement last month.

The coalition threatened to engage in further strike action in November "if Kaiser continues to commit unfair labour practices".

In a statement, Kaiser Permanente said it planned to keep its medical centres running throughout the three-day strike. 219