The incident took place in Sukkur district, where the incoming Pakistan Express on its way from Karachi to Lahore hit the bus, which was heading to Sargodha in central Punjab province.

Iran PressAsia: At least 20 people have been killed and several others injured in a collision between a train and a passenger bus in southwest Pakistan.

The collision occurred in Kandhra town of Sukkur district, located some 500 kilometers (311 miles) from the port city of Karachi, on Friday.

Sukkur Commissioner Shafiq Mahesar confirmed 20 deaths to reporters, fearing a rise in the death toll as the condition of several of those injured appeared to be critical.

Dozens of other passengers were also injured in the accident, the latest in a string of similar incidents in recent years.

"It is a huge tragedy and all administration and police officials are rushing to the site," district commissioner Shafique Ahmed Mahesar told dawn.com.

"It was an unmanned railway crossing as nothing existed there to prevent any traffic," he added. 

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