Iran Press/ Asia: The clashes took place on Wednesday in Jaranwala in the industrial district of Faisalabad, police spokesperson Naveed Ahmad said.
The two Christians were accused of blasphemy, he said, adding they and family members had fled their homes.
Resident Shakil Masih said he heard announcements inciting the people and then saw crowds heading toward the Christian area where blasphemy took place.
The area has been cordoned off as police negotiated with the crowd, provincial police chief Usman Anwar told 'Dawn' website.
The police case against the two Christians is that they found pages of the Quran with some derogatory remarks written in red.
Caretaker Prime Minister Anwar ul Haq Kakar called for stern action against those responsible for Wednesday's violence. "I am gutted by the visuals coming out," he said.
Blasphemy is punishable in Pakistan.
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